What is this infant’s diagnosis after suspected Zika exposure?

This 3-month-old is suspected to have had Zika and toxoplasmosis exposure during pregnancy. Given these factors, and based on the four MRI images and one CT image (bottom) shown, what is her current diagnosis? Are there notable components of the brain that have been spared?

The sequela to this Zika/toxoplasmosis exposure is diffuse cortical dysplasia and dense periventricular calcification. There is also schizencephalic contour abnormality in the left frontal cortex. The posterior fossa and pontomedullary junction regions are spared. For more neuro case review, head to MRI Online.

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